D-Tetrahydropalmatine

• CAT Number: R055934
• CAS Number: 3520-14-7
• Molecular Formula: C21H25NO4
• Molecular Weight: 355.43
• Purity: ≥95%
• Synonyms: (13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
• InChI: InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1
• InChIKey: AEQDJSLRWYMAQI-QGZVFWFLSA-N
• SMILES: COC1=C(C2=C(C[C@@H]3C4=CC(=C(C=C4CCN3C2)OC)OC)C=C1)OC

D-Tetrahydropalmatine (Cat No.:R055934) is a natural isoquinoline alkaloid found in several Corydalis species. It has long been studied for its analgesic, sedative, and anxiolytic properties. D-THP interacts with dopamine receptors, particularly D1 and D2, contributing to its effects on mood regulation, pain relief, and addictive behaviors. Research suggests it may offer therapeutic potential in managing drug dependence, insomnia, and certain neurological disorders. Its relatively low toxicity profile and broad pharmacological activities make D-THP an attractive compound for both traditional medicine and modern biomedical research.