D-Fructose-1,6-bisphosphate (sodium salt hydrate)

• CAT Number: R066788
• CAS Number: 81028-91-3
• Molecular Formula: C6H30Na3O20P2
• Molecular Weight: 553.20
• Purity: ≥95%
• Synonyms: 1,6-bis(dihydrogen phosphate)-D-fructose, trisodium salt, octahydrate
• Storage: Room temperature
• IUPAC Name: trisodium;hydron;[(2R,3R,4S)-2,3,4-trihydroxy-5-oxo-6-phosphonatooxyhexyl] phosphate;octahydrate
• InChI: InChI=1S/C6H14O12P2.3Na.8H2O/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16;;;;;;;;;;;/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16);;;;8*1H2/q;3*+1;;;;;;;;/p-3/t3-,5-,6-;;;;;;;;;;;/m1.........../s1
• InChIKey: BUMXRRGJJDMPRT-PESUWTOCSA-K
• SMILES: [H+].C([C@H]([C@H]([C@@H](C(=O)COP(=O)([O-])[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]

D-Fructose-1,6-bisphosphate (sodium salt hydrate)（Cat No.:R066788）is a central metabolic intermediate involved in glycolysis and gluconeogenesis. It is formed from fructose-6-phosphate by the action of phosphofructokinase, a key regulatory enzyme. This bisphosphorylated sugar plays a crucial role in energy metabolism by facilitating the cleavage into glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. The sodium salt hydrate form enhances its stability and solubility for laboratory use. It is widely employed in biochemical research to investigate enzyme activity, metabolic flux, and regulatory mechanisms in cellular energy pathways, particularly under physiological and pathological conditions.