D-erythro-Sphingosine hydrochloride

• CAT Number: I042518
• CAS Number: 2673-72-5
• Molecular Formula: C18H38ClNO2
• Molecular Weight: 335.95
• Purity: ≥95%
• Synonyms: (E,2S,3R)-2-aminooctadec-4-ene-1,3-diol;hydrochloride
• InChI: InChI=1S/C18H37NO2.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20;/h14-15,17-18,20-21H,2-13,16,19H2,1H3;1H/b15-14+;/t17-,18+;/m0./s1
• InChIKey: YDIHJJLAPMAISR-ZNWYJMOFSA-N
• SMILES: CCCCCCCCCCCCCC=CC(C(CO)N)O.Cl

D-erythro-Sphingosine hydrochloride (Cat No.: I042518) is the hydrochloride salt form of D-erythro-sphingosine, a naturally occurring long-chain amino alcohol that serves as a central backbone of sphingolipids. It plays a key role in cell membrane structure and signaling pathways involved in apoptosis, proliferation, and differentiation. The hydrochloride form enhances solubility and stability for experimental use. D-erythro-Sphingosine hydrochloride is widely employed in lipid metabolism, cancer, and neurobiology research to study sphingolipid functions and to develop potential therapeutic strategies targeting sphingolipid-mediated pathways.

Reference

[1]. Grimm C, et al. Activation of the melastatin-related cation channel TRPM3 by D-erythro-sphingosine [corrected]. Mol Pharmacol. 2005 Mar;67(3):798-805.
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[2]. Chao R, et al. Retinoblastoma protein dephosphorylation induced by D-erythro-sphingosine. J Biol Chem. 1992 Nov 25;267(33):23459-62.
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