D-DOPA - CAS 5796-17-8

D-DOPA (CAS 5796-17-8) is an enantiomer of the dopamine precursor L-DOPA. It can be converted to L-DOPA via sequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner. Intraventricular administration of D-DOPA (200 µg/animal) increases striatal dopamine levels in rats. D-DOPA (20 mg/kg, i.p.) induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA.

Catalog Number: R004391

CAS Number: 5796-17-8

PubChem Substance ID:355158505

Molecular Formula: C9H11NO4

Molecular Weight:197.19

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

Synonyms3-Hydroxy-D-tyrosine; D-3,4-Dihydroxyphenylalanine; (+)-3-(3,4-Dihydroxyphenyl)alanine; (+)-Dopa; D-3-Hydroxytyrosine; β-(3,4-Dihydroxy)-D-phenylalanine;

Property

Molecular Formula: C9H11NO4
Molecular Weight197.19
Purity≥95%
Storage2°C to 8°C

Computed Descriptor

IUPAC Name(2R)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid
InChIInChI=1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m1/s1
InChIKeyWTDRDQBEARUVNC-ZCFIWIBFSA-N
SMILESC1=CC(=C(C=C1CC(C(=O)O)N)O)O