D-a-tert-Butyl-Gly-OH

• CAT Number: R068647
• CAS Number: 26782-71-8
• Molecular Formula: C6H13NO2
• Molecular Weight: 131.17
• Purity: ≥95%
• Synonyms: (2R)-2-amino-3,3-dimethylbutanoic acid
• InChI: InChI=1S/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/t4-/m0/s1
• InChIKey: NPDBDJFLKKQMCM-BYPYZUCNSA-N
• SMILES: CC(C)(C)[C@H](C(=O)O)N

D-a-tert-Butyl-Gly-OH（Cat No.:R068647）is a derivative of glycine, where the amino group is protected by a tert-butyl group at the alpha-carbon position. This modification introduces steric hindrance and enhances the stability of the amino acid, making it useful in peptide synthesis, especially in solid-phase peptide synthesis (SPPS). The tert-butyl group prevents side reactions during peptide formation and allows for selective deprotection when needed. This compound is valuable for introducing modified glycine residues into peptides and studying the impact of bulky groups on peptide folding, stability, and biological activity in pharmaceutical and biochemical research.