Cytosine

• CAT Number: R008895
• CAS Number: 71-30-7
• Molecular Formula: C4H5N3O
• Molecular Weight: 111.10
• Purity: ≥95%
• Synonyms: 6-Amino-2(1H)-pyrimidinone; 4-Amino-1H-pyrimidin-2-one; 4-Amino-2(1H)-pyrimidinone; 4-Amino-2-hydroxypyrimidine; 4-Aminouracil; Cytosinimine; NSC 27787;?
• Target: Endogenous Metabolite
• Storage: -20°C
• IUPAC Name: 6-amino-1H-pyrimidin-2-one
• InChI: InChI=1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
• InChIKey: OPTASPLRGRRNAP-UHFFFAOYSA-N
• SMILES: C1=C(NC(=O)N=C1)N

Cytosine (Cat No.: R008895) is one of the four main nitrogenous bases found in DNA and RNA, classified as a pyrimidine. It pairs with guanine through three hydrogen bonds, contributing to the stability of the nucleic acid structure. Cytosine plays a critical role in genetic coding, replication, and expression. It can undergo methylation to form 5-methylcytosine, which is essential in epigenetic regulation. Due to its susceptibility to deamination, cytosine can mutate to uracil, highlighting its importance in DNA repair and genomic integrity.

Reference

1.Ussery, David W. "Encyclopedia of genetics." (2001).
2.Almohammed, Sawsan, Brian J. Rodriguez, and James H. Rice. "Nucleobase sensing using highly-sensitive surface-enhanced Raman spectroscopy templates comprising organic semiconductor peptide nanotubes and metal nanoparticles." Sensing and Bio-Sensing Research 24 (2019): 100287.
3.Ma, Qiuxiang, Wenzhi Zhou, and Peng Zhang. "Transition from somatic embryo to friable embryogenic callus in cassava: dynamic changes in cellular structure, physiological status, and gene expression profiles." Frontiers in plant science 6 (2015): 824.