Cytochalasin A

• CAT Number: R027618
• CAS Number: 14110-64-6
• Molecular Formula: C29H35NO5
• Molecular Weight: 477.59
• Purity: ≥95%
• Synonyms: (1S,4E,10R,12E,14S,15S,17S,18S,19S)-19-benzyl-15-hydroxy-10,17-dimethyl-16-methylidene-2-oxa-20-azatricyclo[12.7.0.01,18]henicosa-4,12-diene-3,6,21-trione
• InChI: InChI=1S/C29H35NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,23-24,26-27,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,23+,24+,26+,27-,29-/m1/s1
• InChIKey: ZMAODHOXRBLOQO-TZVKRXPSSA-N
• SMILES: C[C@@H]1CCCC(=O)/C=C/C(=O)O[C@]23[C@@H](/C=C/C1)[C@@H](C(=C)[C@H]([C@H]2[C@@H](NC3=O)CC4=CC=CC=C4)C)O

Cytochalasin A（Cat No.:R027618）is a bioactive fungal metabolite of the cytochalasin family, recognized for its strong ability to disrupt actin filament dynamics. By binding to the barbed ends of actin filaments, it inhibits polymerization and alters cytoskeletal organization, leading to changes in cell morphology, adhesion, and motility. Beyond cytoskeletal disruption, Cytochalasin A exhibits antimicrobial, antiviral, and cytotoxic properties, making it an important molecule in natural product and pharmacological research. Its unique mechanism of action provides valuable insights into cell biology, cancer studies, and therapeutic development.