Cytidine 5'-diphosphate disodium

• CAT Number: I025443
• CAS Number: 54394-90-0
• Molecular Formula: C9H15N3O11P2
• Molecular Weight: 403.17
• Purity: 98%
• Synonyms: Cytidine 5'-diphosphate disodium; CDP sodium salt; Cytidine 5'-diphosphate disodium salt; Cytidine diphosphate sodium salt
• Solubility: Soluble in DMSO
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: [(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono hydrogen phosphate
• InChI: InChI=1S/C9H15N3O11P2/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
• InChIKey: ZWIADYZPOWUWEW-XVFCMESISA-N
• SMILES: O=P(OP(O)(O)=O)(OC[C@H]1O[C@@H](N2C=CC(N)=NC2=O)[C@H](O)[C@@H]1O)O

Cytidine 5′-diphosphate disodium(CAT: I025443) is a compound that serves as a substrate for CDP (nucleoside diphosphate) kinase (EC 2.7.4.6). This enzyme catalyzes the phosphorylation of nucleoside diphosphates, including cytidine 5′-diphosphate (CDP), to generate the corresponding nucleoside triphosphates (CTP in this case). CTP is an essential molecule involved in DNA and RNA biosynthesis and serves as a substrate for ribonucleotide reductase, which produces deoxycytidine monophosphate (dCMP) for DNA synthesis. Cytidine 5′-diphosphate disodium plays a crucial role in supporting these biochemical processes by providing the necessary building blocks for nucleic acid synthesis.

Reference

1: Wang L, Pooler AM, Albrecht MA, Wurtman RJ. Dietary uridine-5′-monophosphate supplementation increases potassium-evoked dopamine release and promotes neurite outgrowth in aged rats. J Mol Neurosci. 2005;27(1):137-45. PubMed PMID: 16055952.