For research use only. Not for therapeutic Use.
Cyclopentenyl uracil (Cat No.:I045077) is a synthetic nucleoside analog that functions as a potent inhibitor of uridine and cytidine metabolism. By targeting uridine phosphorylase, CPU disrupts pyrimidine salvage pathways, leading to reduced RNA and DNA synthesis in rapidly dividing cells, including viruses and cancer cells. It enhances the efficacy of chemotherapeutic and antiviral agents by depleting intracellular pyrimidine pools. CPU has been studied for its synergistic effects with fluoropyrimidines and its potential in treating viral infections and malignancies. Its unique mechanism offers a valuable tool in combination therapy strategies.
| CAS Number | 90597-20-9 |
| Synonyms | 1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidine-2,4-dione |
| Molecular Formula | C10H12N2O5 |
| Purity | ≥95% |
| IUPAC Name | 1-[(1R,4R,5S)-4,5-dihydroxy-3-(hydroxymethyl)cyclopent-2-en-1-yl]pyrimidine-2,4-dione |
| InChI | InChI=1S/C10H12N2O5/c13-4-5-3-6(9(16)8(5)15)12-2-1-7(14)11-10(12)17/h1-3,6,8-9,13,15-16H,4H2,(H,11,14,17)/t6-,8-,9+/m1/s1 |
| InChIKey | FCWVOJUKQSHZIV-VDAHYXPESA-N |
| SMILES | C1=CN(C(=O)NC1=O)[C@@H]2C=C([C@H]([C@H]2O)O)CO |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
