Cycloheximide

  • CAT Number: I004513
  • CAS Number: 66-81-9
  • Molecular Formula: C₁₅H₂₃NO₄
  • Molecular Weight: 281.35
  • Purity: ≥95%
Inquiry Now

Cycloheximide(CAT: I004513) is a powerful inhibitor of eukaryotic protein synthesis, commonly used in research to block the translocation step of protein elongation on ribosomes. By halting protein production, Cycloheximide allows scientists to study various cellular processes, including gene expression, protein turnover, and signal transduction. It is particularly useful in experiments examining the regulation of protein stability and degradation. Despite its extensive application in molecular biology and biochemistry, Cycloheximide is highly toxic and not used in clinical treatments. Its cytotoxic properties require careful handling, and it is an essential tool in understanding the dynamics of protein synthesis and degradation in cells.


Catalog Number I004513
CAS Number 66-81-9
Synonyms

4-[(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl]piperidine-2,6-dione

Molecular Formula C₁₅H₂₃NO₄
Purity ≥95%
Target Apoptosis Inducers
Solubility DMSO: ≥ 33 mg/mL
Storage Store at 4°C
IC50 532.5 nM
InChI InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
InChIKey YPHMISFOHDHNIV-FSZOTQKASA-N
SMILES CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C

Request a Quote