Cyclen

• CAT Number: R052761
• CAS Number: 294-90-6
• Molecular Formula: C8H20N4
• Molecular Weight: 172.28
• Purity: ≥95%
• Synonyms: 1,4,7,10-Tetraazacyclododecane; 1,4,7,10-Tetrazacyclododecane; NSC 629374; Tetraaza-12-crown-4
• Target: Disease Research Fields
• Storage: -20°C
• IUPAC Name: 1,4,7,10-tetrazacyclododecane
• InChI: InChI=1S/C8H20N4/c1-2-10-5-6-12-8-7-11-4-3-9-1/h9-12H,1-8H2
• InChIKey: QBPPRVHXOZRESW-UHFFFAOYSA-N
• SMILES: C1CNCCNCCNCCN1

Cyclen(Cat No.: R052761), or 1,4,7,10-tetraazacyclododecane, is a macrocyclic tetraamine with the molecular formula C₈H₂₀N₄. It consists of a 12-membered ring containing four nitrogen atoms positioned at regular intervals, making it a versatile ligand in coordination chemistry. Cyclen strongly binds to metal ions such as lanthanides and transition metals, forming stable chelates. It is widely used in the development of MRI contrast agents, radiopharmaceuticals, and catalysts. Its symmetrical structure and high affinity for cations make it valuable in biomedical and supramolecular applications.