Crassicauline A

• CAT Number: R040022
• CAS Number: 79592-91-9
• Molecular Formula: C35H49NO10
• Molecular Weight: 643.76
• Purity: ≥95%
• Synonyms: [(2R,3R,4R,5S,6S,8R,13S,16S,17R,18R)-8-acetyloxy-11-ethyl-5-hydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate
• IUPAC Name: [(1S,2R,3R,4R,5S,6S,8R,9R,13S,16S,17R,18R)-8-acetyloxy-11-ethyl-5-hydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] 4-methoxybenzoate
• InChI: InChI=1S/C35H49NO10/c1-8-36-17-32(18-40-3)14-13-23(42-5)35-22-15-33(39)24(43-6)16-34(46-19(2)37,26(29(35)36)27(44-7)28(32)35)25(22)30(33)45-31(38)20-9-11-21(41-4)12-10-20/h9-12,22-30,39H,8,13-18H2,1-7H3/t22-,23+,24+,25-,26+,27+,28-,29?,30-,32+,33+,34-,35+/m1/s1
• InChIKey: GAZDXIGXYWVWQX-QVAFJCLZSA-N
• SMILES: CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2[C@H]([C@@H](C31)[C@]5(C[C@@H]([C@]6(C[C@@H]4[C@@H]5[C@H]6OC(=O)C7=CC=C(C=C7)OC)O)OC)OC(=O)C)OC)OC)COC

Crassicauline A（Cat No.:R040022）is a diterpenoid alkaloid isolated from Aconitum species, plants traditionally used in herbal medicine but known for potent toxicity. This compound has drawn scientific interest due to its notable antitumor, analgesic, and anti-inflammatory properties. Crassicauline A demonstrates cytotoxic activity against various cancer cell lines, likely through induction of apoptosis and disruption of cellular signaling pathways. Despite its therapeutic promise, its narrow safety margin requires careful evaluation. As a bioactive alkaloid, Crassicauline A represents both a toxic challenge and a valuable lead for novel drug development.