CQ-Lyso

• CAT Number: I040434
• CAS Number: 2089438-23-1
• Molecular Formula: C30H35N3O3
• Molecular Weight: 485.62
• Purity: ≥95%
• Synonyms: 9-(4-morpholin-4-ylbutoxy)-3-oxa-13,21-diazahexacyclo[15.7.1.02,15.05,14.07,12.021,25]pentacosa-1(25),2(15),5(14),6,8,10,12,16-octaene
• InChI: InChI=1S/C30H35N3O3/c1(9-32-12-15-34-16-13-32)2-14-35-24-7-8-27-22(18-24)17-23-20-36-30-25-6-4-11-33-10-3-5-21(29(25)33)19-26(30)28(23)31-27/h7-8,17-19H,1-6,9-16,20H2
• InChIKey: FEFIUBKGFCHUHF-UHFFFAOYSA-N
• SMILES: C1CC2=CC3=C(C4=C2N(C1)CCC4)OCC5=C3N=C6C=CC(=CC6=C5)OCCCCN7CCOCC7

CQ-Lyso(CAT: I040434) is a lysosome-targeting chromenoquinoline-based fluorescent probe designed for real-time monitoring of lysosomal pH in living cells. Utilizing single-wavelength excitation, CQ-Lyso enables precise and convenient visualization of dynamic pH fluctuations within lysosomes without the need for ratiometric calibration. Its high specificity for lysosomes and excellent fluorescence properties make it ideal for live-cell imaging and cellular physiology studies. CQ-Lyso supports investigations into lysosomal function, acidification, and dysfunction associated with various diseases, including neurodegeneration and cancer. This probe is a powerful tool for researchers studying intracellular organelle environments and pH-dependent biological processes.