For research use only. Not for therapeutic Use.
CP-868388 free base（Cat No.:I006013）is a potent and selective small-molecule inhibitor of platelet-derived growth factor receptors (PDGFR-α and PDGFR-β), tyrosine kinases involved in cell proliferation, angiogenesis, and tumor progression. By blocking PDGFR signaling, CP-868388 disrupts downstream pathways such as PI3K/AKT and MAPK, reducing tumor vascularization and stromal support. It has been investigated in oncology research for its potential to suppress tumor growth and enhance combination therapies. Supplied as a free base form, CP-868388 is a valuable tool for studying PDGFR-driven cancers and therapeutic development.
| CAS Number | 702681-67-2 |
| Synonyms | 2-methyl-2-[3-[(3S)-1-[(4-propan-2-ylphenyl)methoxycarbonyl]piperidin-3-yl]phenoxy]propanoic acid |
| Molecular Formula | C26H33NO5 |
| Purity | ≥95% |
| IUPAC Name | 2-methyl-2-[3-[(3S)-1-[(4-propan-2-ylphenyl)methoxycarbonyl]piperidin-3-yl]phenoxy]propanoic acid |
| InChI | InChI=1S/C26H33NO5/c1-18(2)20-12-10-19(11-13-20)17-31-25(30)27-14-6-8-22(16-27)21-7-5-9-23(15-21)32-26(3,4)24(28)29/h5,7,9-13,15,18,22H,6,8,14,16-17H2,1-4H3,(H,28,29)/t22-/m1/s1 |
| InChIKey | CSLFIHDRJSTULR-JOCHJYFZSA-N |
| SMILES | CC(C)C1=CC=C(C=C1)COC(=O)N2CCC[C@H](C2)C3=CC(=CC=C3)OC(C)(C)C(=O)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
