For research use only. Not for therapeutic Use.
Corynoline（Cat No.:R025346）is a bioactive benzophenanthridine alkaloid isolated from Corydalis bungeana and related species used in traditional Chinese medicine. It exhibits multiple pharmacological effects, including anti-inflammatory, hepatoprotective, anti-angiogenic, and anticancer activities. Corynoline has been reported to inhibit inflammatory signaling pathways, protect liver tissue from toxin-induced injury, and suppress tumor cell proliferation by blocking mitosis and inducing apoptosis. Its ability to modulate cell cycle progression highlights its promise in oncology research. With a unique alkaloid structure, Corynoline represents a valuable natural lead compound for therapeutic development across liver and cancer disorders.
| CAS Number | 18797-79-0 |
| Synonyms | (1R,12S,13R)-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-12-ol |
| Molecular Formula | C21H21NO5 |
| Purity | ≥95% |
| IUPAC Name | (1R,12S,13R)-13,24-dimethyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-12-ol |
| InChI | InChI=1S/C21H21NO5/c1-21-14-3-4-15-19(27-10-24-15)13(14)8-22(2)20(21)12-7-17-16(25-9-26-17)5-11(12)6-18(21)23/h3-5,7,18,20,23H,6,8-10H2,1-2H3/t18-,20+,21-/m0/s1 |
| InChIKey | IQUGPRHKZNCHGC-TYPHKJRUSA-N |
| SMILES | C[C@]12[C@H](CC3=CC4=C(C=C3[C@H]1N(CC5=C2C=CC6=C5OCO6)C)OCO4)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
