Cortodoxone-d2

• CAT Number: I043961
• CAS Number: 1271728-08-5
• Molecular Formula: C21H28D2O4
• Molecular Weight: 348.47
• Purity: ≥95%
• Synonyms: (8R,9S,10R,13S,14S,17R)-17-(2,2-dideuterio-2-hydroxyacetyl)-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
• InChI: InChI=1S/C21H30O4/c1-19-8-5-14(23)11-13(19)3-4-15-16(19)6-9-20(2)17(15)7-10-21(20,25)18(24)12-22/h11,15-17,22,25H,3-10,12H2,1-2H3/t15-,16+,17+,19+,20+,21+/m1/s1/i12D2
• InChIKey: WHBHBVVOGNECLV-FAWVBKBISA-N
• SMILES: [2H]C([2H])(C(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O)O

Cortodoxone-d₂（Cat No.:I043961）is a deuterated analog of cortodoxone, a corticosteroid intermediate involved in the biosynthesis of glucocorticoids such as cortisol. In this labeled form, two hydrogen atoms are replaced by deuterium, making it a valuable internal standard for mass spectrometry and pharmacokinetic studies. Cortodoxone-d₂ is commonly used in research to track steroid metabolism, study enzyme activity, and quantify endogenous corticosteroids with improved precision. Its stable isotope labeling enhances analytical accuracy without altering biological behavior, making it essential in drug development, endocrine studies, and biochemical pathway investigations.