Coptisine Sulfate

• CAT Number: M143277
• CAS Number: 1198398-71-8
• Molecular Formula: C19H15NO8S
• Molecular Weight: 417.39
• Purity: ≥95%
• Synonyms: hydrogen sulfate;5,7,17,19-tetraoxa-13-azoniahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-1(13),2,4(8),9,14,16(20),21,23-octaene
• InChI: InChI=1S/C19H14NO4.H2O4S/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14;1-5(2,3)4/h1-2,5-8H,3-4,9-10H2;(H2,1,2,3,4)/q+1;/p-1
• InChIKey: LHNQVPXIJDUPAX-UHFFFAOYSA-M
• SMILES: C1C[N+]2=C(C=C3C=CC4=C(C3=C2)OCO4)C5=CC6=C(C=C51)OCO6.OS(=O)(=O)[O-]

Coptisine sulfate（Cat No.:M143277）is a quaternary isoquinoline alkaloid derivative found in Coptis chinensis and related medicinal plants. It is valued for its broad pharmacological activities, including anti-inflammatory, antioxidant, antimicrobial, and anticancer effects. Studies indicate that coptisine sulfate can regulate signaling pathways such as AMPK, NF-κB, and MAPK, thereby modulating inflammation, oxidative stress, and tumor progression. It has also demonstrated hepatoprotective and metabolic regulatory properties, making it relevant in liver disease and metabolic disorder research. With its potent bioactivity, coptisine sulfate represents a promising natural compound for therapeutic development.