Congo Red（Cat No.:I009427）, is a synthetic azo dye widely known for its application as a histological stain to detect amyloid deposits in tissues. It appears as a red powder and exhibits a characteristic apple-green birefringence when viewed under polarized light when bound to amyloid fibrils. This property allows for the identification and visualization of amyloidosis-related conditions in medical diagnostics. Congo Red also finds use as a dye in the textile industry for coloring fabrics and fibers. However, its primary significance lies in its role as a histological stain for amyloid detection.
| Catalog Number | I009427 |
| CAS Number | 573-58-0 |
| Synonyms | 3,3/’-[(1,1/’-Biphenyl)-4,4/’-diyl-bis(2,1-diazenediyl)]bis(4-amino-1-naphthalenesulfonic acid) disodium salt |
| Molecular Formula | C32H22N6Na2O6S2 |
| Purity | 95% |
| Target | An amyloid fibril-binding dye |
| Solubility | H?O (~ 5 mg/ml) or DMSO (~5 mg/ml) |
| Storage | RT |
| IUPAC Name | disodium;4-amino-3-[[4-[4-[(1-amino-4-sulfonatonaphthalen-2-yl)diazenyl]phenyl]phenyl]diazenyl]naphthalene-1-sulfonate |
| InChI | InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2 |
| InChIKey | IQFVPQOLBLOTPF-UHFFFAOYSA-L |
| SMILES | C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+] |
