COBRATOXIN (Alpha-)

  • CAT Number: P000009
  • CAS Number: 69344-74-7
  • Molecular Formula: C332 H520 N98 O101 S10
  • Molecular Weight: 7,821
  • Purity: ≥95%
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It is a long chain postsynaptic neurotoxin, antagonist of nicotinic receptor with a high affinity. A 71-amino acid polypeptide with 5 disulfide Bonds, purified from Naja kaouthia snake venom. It is a nicotinic cholinoreceptor antagonist: Kd = 55 pM,homologue of postsynaptically acting toxins.

Catalog Number P000009
CAS Number 69344-74-7
Molecular Formula

C332 H520 N98 O101 S10

Purity 95%
Solubility Well in water and saline
Storage Stable in dry state.Store in a dark place. Keep the solution at -20 °C.
Reference

– Ishikawa Y. et al., Toxicon (1977). 15:477-488<br />
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– Charpentier I. et al., J. of Molecular Recognition (1990). 3:74-81<br />
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– Faure G. et al., Biochemistry (1983). 22:2068-2076<br />
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– Karlsson E. et al.,/Isolation of the principal neurotoxins of Naja naja subspecies from the asian mainland./ Toxicon (1972). 10:217-225<br />
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– Walkinshaw M.D. et al., Proc. Natl. Acad. Sci. USA (1980). 77:2400-2404<br />
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– Betzel C. et al., J. Biol. Chem. (1991). 266:21530-21536<br />
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