CNDAC hydrochloride (Cat No.:M112349) is a nucleoside analog with potent antitumor activity. It works by incorporating into DNA during replication, where its unique cyano group triggers irreversible single-strand breaks that convert into lethal double-strand breaks. This mechanism distinguishes it from other cytidine analogs, as it induces DNA damage without immediate chain termination. CNDAC hydrochloride has shown broad-spectrum activity against solid tumors and hematologic malignancies in preclinical studies, serving as the parent compound for sapacitabine, an orally available prodrug under investigation in cancer therapy.