CN128 hydrochloride

• CAT Number: I015513
• CAS Number: 1335282-05-7
• Molecular Formula: C15H18ClNO3
• Molecular Weight: 295.76
• Purity: ≥95%
• Synonyms: 3-hydroxy-1-[(2R)-1-hydroxy-3-phenylpropan-2-yl]-2-methylpyridin-4-one;hydrochloride
• InChI: InChI=1S/C15H17NO3.ClH/c1-11-15(19)14(18)7-8-16(11)13(10-17)9-12-5-3-2-4-6-12;/h2-8,13,17,19H,9-10H2,1H3;1H/t13-;/m1./s1
• InChIKey: CYFDKXLBMMEWNV-BTQNPOSSSA-N
• SMILES: CC1=C(C(=O)C=CN1[C@H](CC2=CC=CC=C2)CO)O.Cl

CN128 hydrochloride（Cat No.:I015513）is a research-grade small-molecule compound developed as a selective inhibitor of the sodium-calcium exchanger (NCX), a membrane transporter critical for calcium homeostasis. By blocking NCX activity, CN128 alters intracellular calcium flux, impacting processes such as cardiac contractility, neuronal excitability, and muscle physiology. Supplied as the hydrochloride salt, it offers stability and solubility for experimental use. CN128 hydrochloride is widely applied in studies of cardiovascular and neurological disorders, serving as a valuable probe for investigating calcium signaling, arrhythmogenesis, and potential therapeutic interventions targeting calcium regulation.