For research use only. Not for therapeutic Use.
Clobetasol Propionate (Cat No.: A000270) is a highly potent topical corticosteroid used to treat inflammatory skin conditions such as psoriasis, eczema, and dermatitis. It works by suppressing the immune response and reducing inflammation, redness, and itching. Due to its strength, it is typically prescribed for short-term use on small areas of the body. Prolonged or excessive application can lead to side effects like skin thinning or systemic absorption. Clobetasol is available in various formulations, including creams, ointments, gels, and scalp treatments.
CAS Number | 25122-46-7 |
Synonyms | 25122-46-7; Clobetasol 17-propionate; Clobex; Dermovate; Temovate |
Molecular Formula | C25H32ClFO5 |
Purity | ≥95% |
Target | Cytochrome P450 |
Storage | -20°C |
InChI | 1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1 |
InChIKey | CBGUOGMQLZIXBE-XGQKBEPLSA-N |
SMILES | CCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CCl |
Reference | 1: Dolowy M, Kozik V, Bak A, Jampilek J, Barbusinski K, Thomas M, Pyka-Pajak A. A 2: Langasco R, Tanrıverdi ST, Özer Ö, Roldo M, Cossu M, Rassu G, Giunchedi P, 3: Jung KE, Gye JW, Park MK, Park BC. Comparison of the topical FK506 and <br> 5: Şenyiğit T, Sonvico F, Rossi A, Tekmen I, Santi P, Colombo P, Nicoli S, Özer 6: Hidasi AO, Groh KJ, Suter MJ, Schirmer K. Clobetasol propionate causes <br> <br> 9: Sarfaraz Alam M, Ali MS, Zakir F, Alam N, Intakhab Alam M, Ahmad F, Siddiqui <br> |
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