Clindamycin B

• CAT Number: R048472
• CAS Number: 18323-43-8
• Molecular Formula: C₁₇H₃₁ClN₂O₅S
• Molecular Weight: 410.96
• Purity: ≥95%
• Synonyms: Methyl 7-Chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-1-methyl-2-pyrrolidinyl]carbonyl]?amino]-1-thio-L-threo-α-D-galactooctopyranoside; (2S-trans)-Methyl 7-Chloro-6,7,8-?trideoxy-6-[[(4-ethyl-1-methyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-
• Storage: -20°C
• IUPAC Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-4-ethyl-1-methylpyrrolidine-2-carboxamide
• InChI: InChI=1S/C17H31ClN2O5S/c1-5-9-6-10(20(3)7-9)16(24)19-11(8(2)18)15-13(22)12(21)14(23)17(25-15)26-4/h8-15,17,21-23H,5-7H2,1-4H3,(H,19,24)/t8-,9+,10-,11+,12-,13+,14+,15+,17+/m0/s1
• InChIKey: UHQYIIRIOVIPLI-MHXMMLMNSA-N
• SMILES: CC[C@@H]1C[C@H](N(C1)C)C(=O)N[C@@H]([C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl

Clindamycin B（Cat No.:R048472）is a naturally occurring lincosamide antibiotic and a structural analog of clindamycin A, derived from the fermentation of Streptomyces lincolnensis. Though present as a minor component, it shares the core amino acid–sugar structure typical of lincosamides. Clindamycin B exhibits antibacterial activity by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit. It is mainly studied for its role in clindamycin biosynthesis and metabolic profiling, rather than for therapeutic use. Its presence can influence the purity and efficacy of pharmaceutical-grade clindamycin formulations during production.