For research use only. Not for therapeutic Use.
Climbazole(Cat No.:A000681)is an antifungal agent commonly used in dermatological applications to treat fungal infections, including dandruff, seborrheic dermatitis, and athlete’s foot. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting cell membrane integrity and preventing fungal growth. Its broad-spectrum antifungal properties make it an effective treatment against a variety of dermatophytes and yeasts. Climbazole is widely incorporated into topical formulations, such as shampoos, creams, and lotions, due to its mildness and high efficacy in controlling fungal infections.
CAS Number | 38083-17-9 |
Synonyms | 38083-17-9; Baypival; Climbazol; Baysan |
Molecular Formula | C15H17ClN2O2 |
Purity | ≥95% |
Documentation | |
Target | Fungal |
Storage | -20°C |
IUPAC Name | 1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one |
InChI | InChI=1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3 |
InChIKey | OWEGWHBOCFMBLP-UHFFFAOYSA-N |
SMILES | CC(C)(C)C(=O)C(N1C=CN=C1)OC2=CC=C(C=C2)Cl |
Reference | 1: Hawkins S, Adamus J, Chiang CY, Covell E, O/’Leary J, Lee JM. Retinyl 2: Chen G, Ji C, Miao M, Yang K, Luo Y, Hoptroff M, Collins LZ, Janssen HG. 3: Brienza M, Chiron S. Enantioselective reductive transformation of climbazole: <br> 5: Youn HJ, Kim SY, Park M, Jung WH, Lee YW, Choe YB, Ahn KJ. Efficacy and Safety 6: Liu WR, Ying GG, Zhao JL, Liu YS, Hu LX, Yao L, Liang YQ, Tian F. <br> <br> <br> <br> |
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