For research use only. Not for therapeutic Use.
Climbazole(Cat No.:A000681)is an antifungal agent commonly used in dermatological applications to treat fungal infections, including dandruff, seborrheic dermatitis, and athlete’s foot. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting cell membrane integrity and preventing fungal growth. Its broad-spectrum antifungal properties make it an effective treatment against a variety of dermatophytes and yeasts. Climbazole is widely incorporated into topical formulations, such as shampoos, creams, and lotions, due to its mildness and high efficacy in controlling fungal infections.
| CAS Number | 38083-17-9 |
| Synonyms | 38083-17-9; Baypival; Climbazol; Baysan |
| Molecular Formula | C15H17ClN2O2 |
| Purity | ≥95% |
| Documentation | |
| Target | Fungal |
| Storage | -20°C |
| IUPAC Name | 1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one |
| InChI | InChI=1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3 |
| InChIKey | OWEGWHBOCFMBLP-UHFFFAOYSA-N |
| SMILES | CC(C)(C)C(=O)C(N1C=CN=C1)OC2=CC=C(C=C2)Cl |
| Reference | 1: Hawkins S, Adamus J, Chiang CY, Covell E, O/’Leary J, Lee JM. Retinyl 2: Chen G, Ji C, Miao M, Yang K, Luo Y, Hoptroff M, Collins LZ, Janssen HG. 3: Brienza M, Chiron S. Enantioselective reductive transformation of climbazole: <br> 5: Youn HJ, Kim SY, Park M, Jung WH, Lee YW, Choe YB, Ahn KJ. Efficacy and Safety 6: Liu WR, Ying GG, Zhao JL, Liu YS, Hu LX, Yao L, Liang YQ, Tian F. <br> <br> <br> <br> |
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