Clazosentan- CAS 180384-56-9

CAS No.: 180384-56-9

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Clazosentan,180384-56-9
Product Details
For research use only. Not Intended for Therapeutic Use!
Cat No:R059607
Synonyms:

N-[6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-methyl-2-pyridinesulfonamide; Ro 61-1790; VML 588;

Molecular Formula:

C25H23N9O6S

Molecular Weight:577.576
Description:Clazosentan, also known as Ro 61-1790, VML-588 and AXV-034, is a novel and potent endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. Clazosentan is under study in clinical trials for the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH) by Actelion Pharmaceuticals.Clazosentant decreases and reverses cerebral vasospasm after experimental SAH.
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Clazosentan, also known as Ro 61-1790, VML-588 and AXV-034, is a novel and potent endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain injury. Clazosentan is under study in clinical trials for the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH) by Actelion Pharmaceuticals.Clazosentant decreases and reverses cerebral vasospasm after experimental SAH. Clazosentanthas been shown to reduce vasospasm after aneurysmal subarachnoid hemorrhage (aSAH).

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