For research use only. Not for therapeutic Use.
CL264（Cat No.:I045950）is a synthetic small-molecule agonist of Toll-like receptor 7 (TLR7), a key component of the innate immune system. By binding to TLR7, CL264 activates downstream signaling pathways, leading to the production of type I interferons and pro-inflammatory cytokines. It is widely used as a research tool to study antiviral responses, immune modulation, and inflammatory pathways. CL264 has been investigated in the context of cancer immunotherapy, vaccine adjuvant development, and autoimmune disease models. Its potency and selectivity make it valuable for probing TLR7-mediated immune mechanisms.
| CAS Number | 1510712-69-2 |
| Synonyms | 2-[[4-[[6-amino-2-(butylamino)-8-oxo-7H-purin-9-yl]methyl]benzoyl]amino]acetic acid |
| Molecular Formula | C19H23N7O4 |
| Purity | ≥95% |
| IUPAC Name | 2-[[4-[[6-amino-2-(butylamino)-8-oxo-7H-purin-9-yl]methyl]benzoyl]amino]acetic acid |
| InChI | InChI=1S/C19H23N7O4/c1-2-3-8-21-18-24-15(20)14-16(25-18)26(19(30)23-14)10-11-4-6-12(7-5-11)17(29)22-9-13(27)28/h4-7H,2-3,8-10H2,1H3,(H,22,29)(H,23,30)(H,27,28)(H3,20,21,24,25) |
| InChIKey | BXJWQQWEBUICHY-UHFFFAOYSA-N |
| SMILES | CCCCNC1=NC(=C2C(=N1)N(C(=O)N2)CC3=CC=C(C=C3)C(=O)NCC(=O)O)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
