Cl-C6-PEG4-C3-COOH

• CAT Number: I017329
• CAS Number: 2127391-58-4
• Molecular Formula: C18H35ClO6
• Molecular Weight: 382.92
• Purity: ≥95%
• Synonyms: 6-[2-[2-[2-(6-chlorohexoxy)ethoxy]ethoxy]ethoxy]hexanoic acid
• InChI: InChI=1S/C18H35ClO6/c19-9-5-1-2-6-10-22-12-14-24-16-17-25-15-13-23-11-7-3-4-8-18(20)21/h1-17H2,(H,20,21)
• InChIKey: DQFXVBKFPVKFQX-UHFFFAOYSA-N
• SMILES: C(CCCCl)CCOCCOCCOCCOCCCCCC(=O)O

Cl-C6-PEG4-C3-COOH(CAT: I017329) is a bifunctional PEGylated linker designed for use in bioconjugation, drug discovery, and chemical biology applications. It features a chlorinated hexyl (Cl-C6) reactive handle for selective functionalization, a tetraethylene glycol (PEG4) spacer to enhance solubility and flexibility, and a terminal carboxylic acid (–COOH) group for further derivatization or coupling. The PEG4 unit improves aqueous compatibility and reduces steric hindrance, making this linker suitable for the synthesis of PROTACs, antibody–drug conjugates (ADCs), and targeted delivery systems. Cl-C6-PEG4-C3-COOH is a versatile building block for developing bioactive molecules, diagnostic probes, and next-generation therapeutic modalities.