CK2 inhibitor 2

• CAT Number: I045401
• CAS Number: 2641079-92-5
• Molecular Formula: C21H17ClN4O2
• Molecular Weight: 392.84
• Purity: ≥95%

CK2 Inhibitor 2 (Cat No.: I045401) is a selective small-molecule inhibitor of Casein Kinase 2 (CK2), a serine/threonine protein kinase involved in cell survival, proliferation, and DNA repair. Overexpressed in various cancers, CK2 is a promising therapeutic target. CK2 Inhibitor 2 blocks its catalytic activity, leading to apoptosis and reduced tumor growth. It is commonly used in cancer biology research to explore CK2-mediated signaling pathways and assess its potential as a therapeutic target in oncology, especially in hematologic and solid malignancies.

Reference

[1]. Wang Y, et, al. Discovery of 5-(3-Chlorophenylamino)benzo[ c][2,6]naphthyridine Derivatives as Highly Selective CK2 Inhibitors with Potent Cancer Cell Stemness Inhibition. J Med Chem. 2021 Apr 22;64(8):5082-5098.
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