CK156

For research use only. Not for therapeutic Use.

  • CAT Number: I043496
  • CAS Number: 2910938-59-7
  • Molecular Formula: C21H25N5O3
  • Molecular Weight: 395.45
  • Purity: ≥95%
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CK156(Cat No.:I043496)is a selective inhibitor of the enzyme cyclin-dependent kinase 4/6 (CDK4/6), which plays a key role in regulating the cell cycle, particularly in the transition from the G1 to S phase. By inhibiting CDK4/6, CK156 effectively halts uncontrolled cell division, making it a promising therapeutic candidate for the treatment of various cancers, including breast cancer and other CDK4/6-dependent malignancies. This targeted approach can slow tumor growth and enhance the efficacy of existing cancer therapies, offering a potential strategy for managing cancers with dysregulated cell cycle progression.


CAS Number 2910938-59-7
Synonyms

N-tert-butyl-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide

Molecular Formula C21H25N5O3
Purity ≥95%
IUPAC Name N-tert-butyl-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxamide
InChI InChI=1S/C21H25N5O3/c1-21(2,3)25-20(27)15-5-4-14-12-17(15)29-11-10-28-9-7-22-18-6-8-26-19(24-18)16(14)13-23-26/h4-6,8,12-13H,7,9-11H2,1-3H3,(H,22,24)(H,25,27)
InChIKey YCFFONJEHNSECY-UHFFFAOYSA-N
SMILES CC(C)(C)NC(=O)C1=C2C=C(C=C1)C3=C4N=C(C=CN4N=C3)NCCOCCO2
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