For research use only. Not for therapeutic Use.
CJ033466（Cat No.:I010696）is a potent, selective inhibitor of RIPK1 (receptor-interacting protein kinase 1), crucial in regulating inflammatory responses and programmed cell death pathways, including necroptosis. By targeting RIPK1, CJ033466 effectively suppresses inflammation and mitigates excessive immune activation, highlighting its therapeutic potential in inflammatory diseases, autoimmune disorders, and neurodegenerative conditions. This inhibitor’s specificity ensures minimal off-target effects, promoting safer experimental outcomes. Researchers extensively utilize CJ033466 to elucidate RIPK1’s roles in disease mechanisms, offering valuable insights for developing innovative treatments aimed at chronic inflammation, immune dysregulation, and pathological cell death processes.
| CAS Number | 519148-48-2 |
| Synonyms | 5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide |
| Molecular Formula | C19H28ClN5O |
| Purity | ≥95% |
| IUPAC Name | 5-amino-6-chloro-2-methyl-N-[[1-(2-methylpropyl)piperidin-4-yl]methyl]imidazo[1,2-a]pyridine-8-carboxamide |
| InChI | InChI=1S/C19H28ClN5O/c1-12(2)10-24-6-4-14(5-7-24)9-22-19(26)15-8-16(20)17(21)25-11-13(3)23-18(15)25/h8,11-12,14H,4-7,9-10,21H2,1-3H3,(H,22,26) |
| InChIKey | ISKHMDNIWXPUGR-UHFFFAOYSA-N |
| SMILES | CC1=CN2C(=C(C=C(C2=N1)C(=O)NCC3CCN(CC3)CC(C)C)Cl)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
