Citicoline

• CAT Number: I020438
• CAS Number: 987-78-0
• Molecular Formula: C₁₄H₂₆N₄O₁₁P₂
• Molecular Weight: 488.32
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: [[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] 2-(trimethylazaniumyl)ethyl phosphate
• InChI: InChI=1S/C14H26N4O11P2/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/t9-,11-,12-,13-/m1/s1
• InChIKey: RZZPDXZPRHQOCG-OJAKKHQRSA-N
• SMILES: C[N+](C)(C)CCOP(=O)([O-])OP(=O)(O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)O)O

Citicoline (Cat No.: I020438) is the precursor of lecithin biosynthesis, which can promote the biosynthesis of lecithin. Citicoline promotes the restoration and awakening of brain function. It is suitable for disturbance of consciousness caused by traumatic brain injury and stroke sequelae, and also for disturbance of consciousness caused by acute injury of the central nervous system.

Reference

[1]. Davinelli S, et al. Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells. Oxid Med Cell Longev. 2017;2017:2825703.[2]. Karpova MN, et al. Increase of the seizure threshold in C57BL/6 mice after citicoline administration. Bull Exp Biol Med. 2015 Jan;158(3):315-7.