Cinnamtannin B-1

• CAT Number: R067014
• CAS Number: 88082-60-4
• Molecular Formula: C45H36O18
• Molecular Weight: 864.76
• Purity: ≥95%
• Synonyms: (1R,5R,6R,7S,13S,21R)-5,13-bis(3,4-dihydroxyphenyl)-7-[(2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-8-yl]-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol
• InChI: InChI=1S/C45H36O18/c46-18-10-27(54)33-31(11-18)62-45(17-3-6-22(49)26(53)9-17)44(59)38(33)36-32(63-45)14-29(56)35-37(39(58)41(61-43(35)36)16-2-5-21(48)25(52)8-16)34-28(55)13-23(50)19-12-30(57)40(60-42(19)34)15-1-4-20(47)24(51)7-15/h1-11,13-14,30,37-41,44,46-59H,12H2/t30-,37+,38-,39-,40-,41-,44-,45+/m1/s1
• InChIKey: BYSRPHRKESMCPO-LQNPQWRQSA-N
• SMILES: C1C(C(OC2=C1C(=CC(=C2C3C(C(OC4=C3C(=CC5=C4C6C(C(O5)(OC7=CC(=CC(=C67)O)O)C8=CC(=C(C=C8)O)O)O)O)C9=CC(=C(C=C9)O)O)O)O)O)C1=CC(=C(C=C1)O)O)O

Cinnamtannin B-1 (Cat No.: R067014) is a naturally occurring condensed tannin belonging to the proanthocyanidin class, found in cinnamon and other plant sources. It exhibits diverse biological activities, including antioxidant, anti-inflammatory, antimicrobial, and antidiabetic effects. Cinnamtannin B-1 has been studied for its ability to enhance insulin signaling, protect against oxidative stress, and inhibit bacterial growth. It also shows potential cardiovascular benefits by improving endothelial function. This polyphenolic compound is widely investigated in nutritional science, pharmacology, and natural product research for its therapeutic and functional food applications.

Reference

[1]. Meng Li, et al. Cinnamtannin B-1 Prevents Ovariectomy-Induced Osteoporosis via Attenuating Osteoclastogenesis and ROS Generation. Front Pharmacol. 2020 Jul 10;11:1023.
[Content Brief]

[2]. Patrick P Carriere, et al. Cinnamtannin B-1 inhibits cell survival molecules and induces apoptosis in colon cancer.Int J Oncol. 2018 Oct;53(4):1442-1454.
[Content Brief]