Cholecystokinin

• CAT Number: I042548
• CAS Number: 9011-97-6
• Molecular Formula: C167H263N51O52S4
• Molecular Weight: 3945.45
• Purity: ≥95%

Cholecystokinin (Cat No.: I042548) is a peptide hormone produced primarily in the small intestine and the brain. It plays a vital role in digestion and appetite regulation by stimulating gallbladder contraction, pancreatic enzyme secretion, and slowing gastric emptying. CCK also acts as a neurotransmitter, influencing satiety and anxiety-related behaviors. It exerts its effects through CCK1 and CCK2 receptors. Widely studied in gastrointestinal and neurological research, cholecystokinin is essential for understanding gut-brain signaling, digestive physiology, and potential therapeutic targets for obesity and mood disorders.

Reference

[1]. G P Smith, et al. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science. 1981 Aug 28;213(4511):1036-7.
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[2]. R A Liddle, et al. Cholecystokinin cells. Annu Rev Physiol. 1997;59:221-42.
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[3]. Dockray, Graham J. Cholecystokinin. Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):8-12.
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