Cholecystokinin-33 free acid

For research use only. Not for therapeutic Use.

  • CAT Number: I040201
  • Molecular Formula: C167H262N50O53S4
  • Molecular Weight: 3946.43
  • Purity: ≥95%
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Cholecystokinin-33 free acid(CAT: I040201) is a structural analog of Cholecystokinin (CCK-33, HY-P2932) lacking the C-terminal amidation critical for high-affinity receptor binding and full biological activity. The absence of the terminal amide group reduces its potency, making it a valuable tool for investigating the functional role of post-translational modifications in peptide-receptor interactions. This compound is particularly useful in studies exploring the molecular determinants of CCK receptor activation, signaling pathways, and the physiological relevance of amidation in gastrointestinal and neurological systems. It serves as a comparative control for elucidating the structure–activity relationship of CCK family peptides in both in vitro and in vivo models.

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