Chloroquine Diphosphate - CAS 50-63-5

Chloroquine phosphate is an antimalarial 4-aminoquinoline compound used to inhibit growth of malarial parasites and treat malarial infections.
Chloroquine enters a malarial parasite and binds to hemozoin, a non-toxic polymer formed from the parasite in an infected red blood cell. The chloroquine:hemozin complex interferes with normal membrane function leading to build-up of chloroquine:hemozin complexes and ultimately, cell lysis.

Catalog Number: A000578

CAS Number: 50-63-5

PubChem Substance ID:355038045

Molecular Formula: C₁₈H₂₆ClN₃·2H₃PO₄

Molecular Weight:515.86

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

• Synonyms: NA

Property

• Molecular Formula: C₁₈H₂₆ClN₃·2H₃PO₄
• Molecular Weight: 515.86
• Target: Autophagy
• Solubility: Limited solubility
• Purity: ≥95%
• Storage: Desiccate at RT
• MDL: MFCD00069852

Computed Descriptor

• InChI: InChI=1S/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4)
• InChIKey: QKICWELGRMTQCR-UHFFFAOYSA-N
• SMILES: CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl.OP(=O)(O)O.OP(=O)(O)O