Chloroprocaine hydrochloride

• CAT Number: A000147
• CAS Number: 3858-89-7
• Molecular Formula: C13H20Cl2N2O2
• Molecular Weight: 307.22
• Purity: ≥95%
• Synonyms: 2-(diethylamino)ethyl 4-amino-2-chlorobenzoate;hydrochloride
• InChI: InChI=1S/C13H19ClN2O2.ClH/c1-3-16(4-2)7-8-18-13(17)11-6-5-10(15)9-12(11)14;/h5-6,9H,3-4,7-8,15H2,1-2H3;1H
• InChIKey: SZKQYDBPUCZLRX-UHFFFAOYSA-N
• SMILES: CCN(CC)CCOC(=O)C1=C(C=C(C=C1)N)Cl.Cl

Chloroprocaine hydrochloride（Cat No.:A000147）is a local anesthetic drug with the molecular formula C13H20ClNO2·HCl, commonly used for infiltration, nerve block, and epidural anesthesia. It is an ester-type anesthetic, structurally related to procaine, but with a chlorine atom that enhances its potency and reduces systemic toxicity. Chloroprocaine has a rapid onset and short duration of action due to fast hydrolysis by plasma esterases. It appears as a white crystalline powder, soluble in water, and is typically administered as a sterile solution. It is especially favored for short surgical procedures and obstetric anesthesia.

Reference

[1]. H Kutchai, et al. Inhibition of the Na,K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43(4):399-403.
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[2]. Chloroprocaine HCl Injection.