Chlorin e6 trimethyl ester

• CAT Number: I044666
• CAS Number: 35038-32-5
• Molecular Formula: C37H42N4O6
• Molecular Weight: 638.75
• Purity: ≥95%
• Synonyms: methyl (17S,18S)-12-ethenyl-7-ethyl-20-(2-methoxy-2-oxoethyl)-18-(3-methoxy-3-oxopropyl)-3,8,13,17-tetramethyl-17,18,22,23-tetrahydroporphyrin-2-carboxylate
• InChI: InChI=1S/C37H42N4O6/c1-10-22-18(3)26-15-28-20(5)24(12-13-32(42)45-7)35(40-28)25(14-33(43)46-8)36-34(37(44)47-9)21(6)29(41-36)17-31-23(11-2)19(4)27(39-31)16-30(22)38-26/h10,15-17,20,24,38-39H,1,11-14H2,2-9H3/t20-,24-/m0/s1
• InChIKey: SLLLYKPHDYTLSL-RDPSFJRHSA-N
• SMILES: CCC1=C(C2=CC3=C(C(=C(N3)C=C4[C@H]([C@@H](C(=N4)C(=C5C(=C(C(=N5)C=C1N2)C)C(=O)OC)CC(=O)OC)CCC(=O)OC)C)C)C=C)C

Chlorin e6 trimethyl ester（Cat No.:I044666）is a lipophilic derivative of chlorin e6, a second-generation photosensitizer used in photodynamic therapy (PDT). The trimethyl ester modification enhances its solubility in organic solvents and improves cellular uptake, making it suitable for experimental and therapeutic applications. Upon activation by light, chlorin e6 trimethyl ester generates reactive oxygen species (ROS), inducing selective cytotoxicity in targeted cells, including cancer cells. It is widely used in preclinical research for tumor imaging, PDT studies, and photochemical internalization. This compound is valuable for exploring light-activated therapeutic strategies in oncology and beyond.