Chlorahololide C

• CAT Number: R066104
• CAS Number: 1007859-25-7
• Molecular Formula: C33H36O9
• Molecular Weight: 576.63
• Purity: ≥95%
• Synonyms: methyl 2-[(2S,7R,8S,10S,12R,13S,14S,16S,17S,19R,20S,21R)-7-acetyloxy-16,21-dihydroxy-5,13,20-trimethyl-9-methylidene-4,22-dioxo-3-oxaoctacyclo[14.7.1.02,6.02,14.08,13.010,12.017,19.020,24]tetracosa-1(24),5-dien-23-ylidene]propanoate
• IUPAC Name: methyl (2Z)-2-[(2S,7R,8S,10S,12R,13S,14S,16S,17S,19R,20S,21R)-7-acetyloxy-16,21-dihydroxy-5,13,20-trimethyl-9-methylidene-4,22-dioxo-3-oxaoctacyclo[14.7.1.02,6.02,14.08,13.010,12.017,19.020,24]tetracosa-1(24),5-dien-23-ylidene]propanoate
• InChI: InChI=1S/C33H36O9/c1-11-15-8-16(15)30(5)19-10-32(39)18-9-17(18)31(6)26(32)23(20(24(35)27(31)36)12(2)28(37)40-7)33(19)22(13(3)29(38)42-33)25(21(11)30)41-14(4)34/h15-19,21,25,27,36,39H,1,8-10H2,2-7H3/b20-12-/t15-,16-,17-,18+,19+,21-,25-,27+,30-,31+,32+,33-/m1/s1
• InChIKey: FUWHPWXSVUDXDS-XMJAEXKHSA-N
• SMILES: CC1=C2[C@@H]([C@H]3C(=C)[C@H]4C[C@H]4[C@@]3([C@H]5[C@@]2(C\6=C7[C@]([C@@H]8C[C@@H]8[C@]7(C5)O)([C@H](C(=O)/C6=C(/C)\C(=O)OC)O)C)OC1=O)C)OC(=O)C

Chlorahololide C（Cat No.:R066104）is a unique sesquiterpene lactone isolated from the medicinal plant Chloranthus holostegius. It features a distinctive lindenane-type skeleton with multiple oxygenated functionalities, contributing to its potent biological activities. Studies have shown that chlorahololide C exhibits significant anti-cancer properties, particularly by inducing apoptosis and inhibiting cell proliferation in various tumor cell lines. Its mechanism of action is believed to involve the modulation of mitochondrial pathways and cell cycle arrest. As a novel natural compound, chlorahololide C offers promising potential for development in anticancer and pharmacological research.