Cgp 52432

• CAT Number: I006050
• CAS Number: 139667-74-6
• Molecular Formula: C15H24Cl2NO4P
• Molecular Weight: 384.23
• Purity: ≥95%
• Synonyms: Cgp 52432; Cgp52432; Cgp52432.;Phosphinic acid, (3-(((3,4-dichlorophenyl)methyl)amino)propyl)(diethoxymethyl)-
• Target: Neuronal Signaling
• Solubility: Soluble in DMSO, not in water
• Storage: Desiccate at +4℃
• IUPAC Name: 3-[(3,4-dichlorophenyl)methylamino]propyl-(diethoxymethyl)phosphinic acid
• InChI: InChI=1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
• InChIKey: GJZVQXWEIYRHBE-UHFFFAOYSA-N
• SMILES: CCOC(OCC)P(=O)(CCCNCC1=CC(=C(C=C1)Cl)Cl)O

Cgp 52432 (CAT: I006050) is a selective antagonist of the gamma-aminobutyric acid type A (GABA-A) receptor. GABA-A receptors are ion channels that mediate inhibitory neurotransmission in the central nervous system. By blocking the activity of GABA-A receptors, Cgp 52432 interferes with the binding of GABA, the main inhibitory neurotransmitter, and disrupts inhibitory signaling in the brain. This antagonist effect on GABA-A receptors may have implications in the modulation of neuronal excitability and the treatment of various neurological and psychiatric disorders.