For research use only. Not for therapeutic Use.
Cefotiam hexetil hydrochloride(Cat No.:R013099)is an orally active prodrug of cefotiam, a broad-spectrum, second-generation cephalosporin antibiotic. Designed for improved gastrointestinal absorption, it is rapidly hydrolyzed in vivo to release the active form, cefotiam. The compound inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis. It demonstrates strong activity against Gram-positive and Gram-negative organisms, including Haemophilus influenzae and Enterobacteriaceae. Clinically, cefotiam hexetil hydrochloride is used for respiratory tract, urinary tract, and soft tissue infections, offering reliable efficacy and oral convenience.
CAS Number | 95789-30-3 |
Synonyms | 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;dihydrochloride |
Molecular Formula | C27H39Cl2N9O7S3 |
Purity | ≥95% |
IUPAC Name | 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;dihydrochloride |
InChI | InChI=1S/C27H37N9O7S3.2ClH/c1-15(42-27(40)43-18-7-5-4-6-8-18)41-24(39)21-16(13-46-26-31-32-33-35(26)10-9-34(2)3)12-44-23-20(22(38)36(21)23)30-19(37)11-17-14-45-25(28)29-17;;/h14-15,18,20,23H,4-13H2,1-3H3,(H2,28,29)(H,30,37);2*1H/t15?,20-,23-;;/m1../s1 |
InChIKey | FFSANQNELHESQJ-LWBICVDYSA-N |
SMILES | CC(OC(=O)C1=C(CS[C@H]2N1C(=O)[C@H]2NC(=O)CC3=CSC(=N3)N)CSC4=NN=NN4CCN(C)C)OC(=O)OC5CCCCC5.Cl.Cl |
Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |