Cefotiam hexetil hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: R013099
  • CAS Number: 95789-30-3
  • Molecular Formula: C27H39Cl2N9O7S3
  • Molecular Weight: 768.76
  • Purity: ≥95%
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Cefotiam hexetil hydrochloride(Cat No.:R013099)is an orally active prodrug of cefotiam, a broad-spectrum, second-generation cephalosporin antibiotic. Designed for improved gastrointestinal absorption, it is rapidly hydrolyzed in vivo to release the active form, cefotiam. The compound inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to cell lysis. It demonstrates strong activity against Gram-positive and Gram-negative organisms, including Haemophilus influenzae and Enterobacteriaceae. Clinically, cefotiam hexetil hydrochloride is used for respiratory tract, urinary tract, and soft tissue infections, offering reliable efficacy and oral convenience.


CAS Number 95789-30-3
Synonyms

1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;dihydrochloride

Molecular Formula C27H39Cl2N9O7S3
Purity ≥95%
IUPAC Name 1-cyclohexyloxycarbonyloxyethyl (6R,7R)-7-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-3-[[1-[2-(dimethylamino)ethyl]tetrazol-5-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;dihydrochloride
InChI InChI=1S/C27H37N9O7S3.2ClH/c1-15(42-27(40)43-18-7-5-4-6-8-18)41-24(39)21-16(13-46-26-31-32-33-35(26)10-9-34(2)3)12-44-23-20(22(38)36(21)23)30-19(37)11-17-14-45-25(28)29-17;;/h14-15,18,20,23H,4-13H2,1-3H3,(H2,28,29)(H,30,37);2*1H/t15?,20-,23-;;/m1../s1
InChIKey FFSANQNELHESQJ-LWBICVDYSA-N
SMILES CC(OC(=O)C1=C(CS[C@H]2N1C(=O)[C@H]2NC(=O)CC3=CSC(=N3)N)CSC4=NN=NN4CCN(C)C)OC(=O)OC5CCCCC5.Cl.Cl
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