CDK5-IN-3

• CAT Number: I044006
• CAS Number: 2639542-32-6
• Molecular Formula: C22H26N4O
• Molecular Weight: 362.47
• Purity: ≥95%
• Synonyms: (1R)-1-(7-anilino-1,6-naphthyridin-2-yl)-1-(1-methylpiperidin-4-yl)ethanol
• InChI: InChI=1S/C22H26N4O/c1-22(27,17-10-12-26(2)13-11-17)20-9-8-16-15-23-21(14-19(16)25-20)24-18-6-4-3-5-7-18/h3-9,14-15,17,27H,10-13H2,1-2H3,(H,23,24)/t22-/m1/s1
• InChIKey: MLZPRAPIZUZUNO-JOCHJYFZSA-N
• SMILES: C[C@@](C1CCN(CC1)C)(C2=NC3=CC(=NC=C3C=C2)NC4=CC=CC=C4)O

CDK5-IN-3（Cat No.:I044006）is a selective inhibitor targeting cyclin-dependent kinase 5 (CDK5), an enzyme involved in regulating neuronal function and implicated in neurodegenerative diseases such as Alzheimer’s disease. CDK5 plays a crucial role in the phosphorylation of key proteins, and its dysregulation is associated with neuronal damage and tau pathology. CDK5-IN-3 aims to inhibit CDK5 activity, potentially slowing or preventing neurodegeneration. This compound is being studied for its therapeutic potential in treating Alzheimer’s and other cognitive disorders by modulating CDK5-related pathways, offering hope for improved treatments in neurodegenerative diseases.