For research use only. Not for therapeutic Use.
CDE-096（Cat No.:I024276）is a selective small-molecule antagonist of the P2X7 receptor, a ligand-gated ion channel activated by extracellular ATP and implicated in inflammation, immune responses, and cell death. By inhibiting P2X7, CDE-096 blocks downstream signaling pathways, including NLRP3 inflammasome activation and interleukin-1β (IL-1β) release. It has shown promise in preclinical models of inflammatory and neurodegenerative diseases, such as multiple sclerosis and Alzheimer’s disease. CDE-096 is used in research to study purinergic signaling and its role in immune regulation, making it a valuable tool for developing anti-inflammatory and neuroprotective therapies.
| CAS Number | 1228357-04-7 |
| Synonyms | [3-[[3-(trifluoromethyl)phenoxy]carbonylamino]-2-(3,4,5-trihydroxybenzoyl)oxypropyl] 3,4,5-trihydroxybenzoate |
| Molecular Formula | C25H20F3NO12 |
| Purity | ≥95% |
| IUPAC Name | [3-[[3-(trifluoromethyl)phenoxy]carbonylamino]-2-(3,4,5-trihydroxybenzoyl)oxypropyl] 3,4,5-trihydroxybenzoate |
| InChI | InChI=1S/C25H20F3NO12/c26-25(27,28)13-2-1-3-14(8-13)41-24(38)29-9-15(40-23(37)12-6-18(32)21(35)19(33)7-12)10-39-22(36)11-4-16(30)20(34)17(31)5-11/h1-8,15,30-35H,9-10H2,(H,29,38) |
| InChIKey | OXWKLJPAKUDPJY-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)OC(=O)NCC(COC(=O)C2=CC(=C(C(=C2)O)O)O)OC(=O)C3=CC(=C(C(=C3)O)O)O)C(F)(F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
