For research use only. Not for therapeutic Use.
CDDO-dhTFEA (Cat No.:I018180) is a synthetic oleanane triterpenoid analog with potent anti-inflammatory, antioxidant, and anticancer properties. It functions as an activator of the Nrf2/ARE signaling pathway, enhancing cellular defense against oxidative stress while inhibiting NF-κB–mediated inflammatory responses. CDDO-dhTFEA has been studied for its ability to induce apoptosis, suppress tumor cell proliferation, and modulate immune responses. Its pharmacological profile makes it a valuable research tool in cancer, inflammation, and neurodegenerative disease studies, offering insights into redox biology and therapeutic development strategies.
| CAS Number | 1191265-33-4 |
| Synonyms | (4aS,6aR,6aR,6bR,8aR,12aR,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-N-(2,2,2-trifluoroethyl)-1,3,4,5,6,6a,7,8,8a,13,14a,14b-dodecahydropicene-4a-carboxamide |
| Molecular Formula | C33H45F3N2O3 |
| Purity | ≥95% |
| IUPAC Name | (4aS,6aR,6aR,6bR,8aR,12aR,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-N-(2,2,2-trifluoroethyl)-1,3,4,5,6,6a,7,8,8a,13,14a,14b-dodecahydropicene-4a-carboxamide |
| InChI | InChI=1S/C33H45F3N2O3/c1-27(2)10-12-32(26(41)38-18-33(34,35)36)13-11-31(7)24(20(32)16-27)21(39)14-23-29(5)15-19(17-37)25(40)28(3,4)22(29)8-9-30(23,31)6/h15,20,22-24H,8-14,16,18H2,1-7H3,(H,38,41)/t20-,22-,23+,24-,29-,30+,31+,32-/m0/s1 |
| InChIKey | RMYWYZJDSBWZHH-BFGQVZSYSA-N |
| SMILES | C[C@@]12CC[C@@H]3[C@@]([C@H]1CC(=O)[C@H]4[C@]2(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)NCC(F)(F)F)C)(C=C(C(=O)C3(C)C)C#N)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
