CDC25B-IN-2

• CAT Number: I044684
• CAS Number: 134271-74-2
• Molecular Formula: C15H12N2O3
• Molecular Weight: 268.27
• Purity: ≥95%
• IUPAC Name: (E)-1-(2-aminophenyl)-3-(3-nitrophenyl)prop-2-en-1-one
• InChI: InChI=1S/C15H12N2O3/c16-14-7-2-1-6-13(14)15(18)9-8-11-4-3-5-12(10-11)17(19)20/h1-10H,16H2/b9-8+
• InChIKey: LRMPAVQDWGDIBD-CMDGGOBGSA-N
• SMILES: C1=CC=C(C(=C1)C(=O)/C=C/C2=CC(=CC=C2)[N+](=O)[O-])N

CDC25B-IN-2（Cat No.:I044684）is a selective small-molecule inhibitor of CDC25B phosphatase, an enzyme involved in cell cycle progression by activating cyclin-dependent kinases (CDKs), particularly at the G2/M checkpoint. Overexpression of CDC25B is associated with various cancers, promoting uncontrolled cell proliferation. CDC25B-IN-2 disrupts this process by inhibiting the phosphatase activity, leading to cell cycle arrest and apoptosis in tumor cells. It has shown promising results in preclinical cancer models, making it a valuable candidate for further exploration in oncology research. CDC25B-IN-2 supports targeted therapeutic strategies aimed at cell cycle dysregulation in cancer.