For research use only. Not for therapeutic Use.
CC260（Cat No.:I024226）is a selective small-molecule inhibitor of casein kinase 1 delta (CK1δ), a serine/threonine kinase involved in regulating circadian rhythms, cell cycle progression, and signal transduction. By targeting CK1δ, CC260 modulates phosphorylation of substrates such as PER proteins, influencing circadian clock function and cellular proliferation. It has shown potential in preclinical models for treating sleep disorders, neurodegenerative diseases, and certain cancers where CK1δ is dysregulated. CC260 serves as a valuable research tool for dissecting CK1δ-dependent pathways and supports therapeutic exploration in chronobiology, oncology, and neurobiology.
| CAS Number | 2411088-26-9 |
| Synonyms | (7R)-8-cyclopentyl-7-(cyclopentylmethyl)-2-(3,5-dichloro-4-hydroxyanilino)-5-methyl-7H-pteridin-6-one |
| Molecular Formula | C24H29Cl2N5O2 |
| Purity | ≥95% |
| IUPAC Name | (7R)-8-cyclopentyl-7-(cyclopentylmethyl)-2-(3,5-dichloro-4-hydroxyanilino)-5-methyl-7H-pteridin-6-one |
| InChI | InChI=1S/C24H29Cl2N5O2/c1-30-20-13-27-24(28-15-11-17(25)21(32)18(26)12-15)29-22(20)31(16-8-4-5-9-16)19(23(30)33)10-14-6-2-3-7-14/h11-14,16,19,32H,2-10H2,1H3,(H,27,28,29)/t19-/m1/s1 |
| InChIKey | AEZJZTFWCDAUDF-LJQANCHMSA-N |
| SMILES | CN1C2=CN=C(N=C2N([C@@H](C1=O)CC3CCCC3)C4CCCC4)NC5=CC(=C(C(=C5)Cl)O)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
