CC-885-CH2-PEG1-NH-CH3

• CAT Number: I045129
• CAS Number: 2722698-03-3
• Molecular Formula: C26H30ClN5O5
• Molecular Weight: 528.00
• Purity: ≥95%
• Synonyms: 1-[3-chloro-4-[2-[2-(methylamino)ethoxy]ethyl]phenyl]-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea
• InChI: InChI=1S/C26H30ClN5O5/c1-28-9-11-37-10-8-17-3-4-19(13-21(17)27)30-26(36)29-14-16-2-5-20-18(12-16)15-32(25(20)35)22-6-7-23(33)31-24(22)34/h2-5,12-13,22,28H,6-11,14-15H2,1H3,(H2,29,30,36)(H,31,33,34)
• InChIKey: CHFAZLBAAPOQTD-UHFFFAOYSA-N
• SMILES: CNCCOCCC1=C(C=C(C=C1)NC(=O)NCC2=CC3=C(C=C2)C(=O)N(C3)C4CCC(=O)NC4=O)Cl

CC-885-CH₂-PEG1-NH-CH₃（Cat No.:I045129）is a synthetic derivative of CC-885, a cereblon (CRBN)-binding molecular glue that induces targeted protein degradation via the ubiquitin-proteasome system. This modified analog features a PEG1 linker and a terminal methylamino group, facilitating conjugation or functionalization in chemical biology applications. Like its parent compound, it recruits neosubstrates—such as GSPT1—to CRBN, promoting their ubiquitination and degradation. The compound is valuable in the study of targeted protein degradation, molecular glue design, and drug discovery. Supplied for advanced research in proteolysis-targeting strategies and degrader development.