For research use only. Not for therapeutic Use.
CBP/p300 Ligand 2（Cat No.:I044620）is a selective small-molecule ligand that targets the transcriptional coactivators CBP (CREB-binding protein) and p300, which regulate gene expression through histone acetylation. By binding to the bromodomain of CBP/p300, this ligand modulates chromatin structure and transcriptional activity, making it a valuable tool for studying epigenetic regulation. CBP/p300 Ligand 2 is used in research exploring cancer, inflammation, and neurological disorders where dysregulated acetylation plays a role. Its specificity and potency support its application in dissecting transcriptional mechanisms and in the development of epigenetic-based therapeutic strategies.
| CAS Number | 2484741-78-6 |
| Synonyms | 3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-piperidin-4-yl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide |
| Molecular Formula | C27H34F2N8O |
| Purity | ≥95% |
| IUPAC Name | 3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-piperidin-4-yl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide |
| InChI | InChI=1S/C27H34F2N8O/c1-30-27(38)35-11-7-23-22(16-35)26(33-37(23)19-5-8-31-9-6-19)36-10-3-4-17-12-20(18-14-32-34(2)15-18)21(25(28)29)13-24(17)36/h12-15,19,25,31H,3-11,16H2,1-2H3,(H,30,38) |
| InChIKey | XFGMGPKELLCGAA-UHFFFAOYSA-N |
| SMILES | CNC(=O)N1CCC2=C(C1)C(=NN2C3CCNCC3)N4CCCC5=CC(=C(C=C54)C(F)F)C6=CN(N=C6)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
