CBP/p300-IN-3

• CAT Number: I018063
• CAS Number: 2299226-01-8
• Molecular Formula: C24H29N7O
• Molecular Weight: 431.53
• Purity: ≥95%
• Synonyms: 2-[6-(diethylamino)pyridin-3-yl]-1-[(1-ethylpyrazol-3-yl)methyl]-N-methylbenzimidazole-5-carboxamide
• IUPAC Name: 2-[6-(diethylamino)-3-pyridinyl]-1-[(1-ethylpyrazol-3-yl)methyl]-N-methylbenzimidazole-5-carboxamide
• InChI: InChI=1S/C24H29N7O/c1-5-29(6-2)22-11-9-18(15-26-22)23-27-20-14-17(24(32)25-4)8-10-21(20)31(23)16-19-12-13-30(7-3)28-19/h8-15H,5-7,16H2,1-4H3,(H,25,32)
• InChIKey: LYVJDLHFTGYNAV-UHFFFAOYSA-N
• SMILES: CCN1C=CC(=N1)CN2C3=C(C=C(C=C3)C(=O)NC)N=C2C4=CN=C(C=C4)N(CC)CC

CBP/p300-IN-3（Cat No.:I018063）is a selective small-molecule inhibitor targeting the histone acetyltransferases CBP and p300, key transcriptional co-activators that regulate gene expression through epigenetic modification. By blocking acetyltransferase activity, CBP/p300-IN-3 suppresses histone acetylation, thereby modulating chromatin structure and transcriptional programs involved in cancer progression, inflammation, and metabolic regulation. This compound is a valuable research tool for dissecting CBP/p300-dependent signaling pathways, investigating tumor biology, and exploring novel therapeutic strategies in oncology and immunology. Its potency and selectivity make it suitable for mechanistic and preclinical studies.