For research use only. Not for therapeutic Use.
CAY10698 (Cat No.: R065857) is a synthetic small-molecule inhibitor of cyclooxygenase-2 (COX-2), an inducible enzyme involved in prostaglandin synthesis and inflammatory signaling. By selectively blocking COX-2 activity, CAY10698 reduces the production of pro-inflammatory mediators while sparing COX-1, thereby minimizing gastrointestinal side effects commonly associated with non-selective NSAIDs. It is primarily used as a biochemical tool in research to study inflammation, pain pathways, and cancer-related prostaglandin signaling. CAY10698 highlights the therapeutic potential of selective COX-2 inhibition in inflammatory and oncological conditions.
| CAS Number | 684236-01-9 |
| Synonyms | 4-[(2-hydroxy-3-methoxyphenyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide |
| Molecular Formula | C17H17N3O4S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H17N3O4S2/c1-24-15-4-2-3-12(16(15)21)11-19-13-5-7-14(8-6-13)26(22,23)20-17-18-9-10-25-17/h2-10,19,21H,11H2,1H3,(H,18,20) |
| InChIKey | CENSVXZQMJBVHY-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC(=C1O)CNC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3 |
| Reference | [1]. David J. Maloney, et al. 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
