Cathepsin inhibitor 1

• CAT Number: I010449
• CAS Number: 225120-65-0
• Molecular Formula: C20H24ClN5O2
• Molecular Weight: 401.89
• Purity: ≥95%
• Synonyms: 5-tert-butyl-N-[(2S)-3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl]-2-methylpyrazole-3-carboxamide
• InChI: InChI=1S/C20H24ClN5O2/c1-20(2,3)17-12-16(26(4)25-17)19(28)24-15(18(27)23-9-8-22)11-13-6-5-7-14(21)10-13/h5-7,10,12,15H,9,11H2,1-4H3,(H,23,27)(H,24,28)/t15-/m0/s1
• InChIKey: MZRVIHRERYCHBL-HNNXBMFYSA-N
• SMILES: CC(C)(C)C1=NN(C(=C1)C(=O)N[C@@H](CC2=CC(=CC=C2)Cl)C(=O)NCC#N)C

Cathepsin Inhibitor 1（Cat No.:I010449）is a potent, cell-permeable compound that selectively inhibits cathepsins, a family of lysosomal cysteine proteases involved in protein degradation, antigen processing, and apoptosis. By targeting cathepsin activity, this inhibitor is widely used in research to study protease-related pathways in cancer, inflammation, and neurodegenerative diseases. Cathepsin Inhibitor 1 helps elucidate the role of cathepsins in tumor invasion, metastasis, and immune regulation. Its high specificity and effectiveness make it a valuable tool for developing therapeutic strategies aimed at modulating protease activity in pathological conditions involving excessive proteolysis.